Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

L1cam  L1 cell adhesion molecule   (Synonyms: CD171, L1, L1-NCAM, NCAM-L1)
Results	Reference
1	J:225119 Aida T, Ito Y, Takahashi YK, Tanaka K, Overstimulation of NMDA receptors impairs early brain development in vivo. PLoS One. 2012;7(5):e36853
1	J:195145 Amaniti EM, Hasenpusch-Theil K, Li Z, Magnani D, Kessaris N, Mason JO, Theil T, Gli3 is required in Emx1(+) progenitors for the development of the corpus callosum. Dev Biol. 2013 Apr 15;376(2):113-24
1	J:272349 Baba K, Yoshida W, Toriyama M, Shimada T, Manning CF, Saito M, Kohno K, Trimmer JS, Watanabe R, Inagaki N, Gradient-reading and mechano-effector machinery for netrin-1-induced axon guidance. Elife. 2018 Aug 7;7:e34593
1	J:183848 Benadiba C, Magnani D, Niquille M, Morle L, Valloton D, Nawabi H, Ait-Lounis A, Otsmane B, Reith W, Theil T, Hornung JP, Lebrand C, Durand B, The ciliogenic transcription factor RFX3 regulates early midline distribution of guidepost neurons required for corpus callosum development. PLoS Genet. 2012 Mar;8(3):e1002606
1*	J:60855 Birgbauer E, Cowan CA, Sretavan DW, Henkemeyer M, Kinase independent function of EphB receptors in retinal axon pathfinding to the optic disc from dorsal but not ventral retina. Development. 2000 Mar;127(6):1231-41
1	J:295421 Brosig A, Fuchs J, Ipek F, Kroon C, Schrotter S, Vadhvani M, Polyzou A, Ledderose J, van Diepen M, Holzhutter HG, Trimbuch T, Gimber N, Schmoranzer J, Lieberam I, Rosenmund C, Spahn C, Scheerer P, Szczepek M, Leondaritis G, Eickholt BJ, The Axonal Membrane Protein PRG2 Inhibits PTEN and Directs Growth to Branches. Cell Rep. 2019 Nov 12;29(7):2028-2040.e8
1	J:68904 Brouns MR, Matheson SF, Settleman J, p190 RhoGAP is the principal Src substrate in brain and regulates axon outgrowth, guidance and fasciculation. Nat Cell Biol. 2001 Apr;3(4):361-7
1	J:311855 Brudvig JJ, Cain JT, Schmidt-Grimminger GG, Stumpo DJ, Roux KJ, Blackshear PJ, Weimer JM, MARCKS Is Necessary for Netrin-DCC Signaling and Corpus Callosum Formation. Mol Neurobiol. 2018 Nov;55(11):8388-8402
1*	J:150043 Bush JO, Soriano P, Ephrin-B1 regulates axon guidance by reverse signaling through a PDZ-dependent mechanism. Genes Dev. 2009 Jul 1;23(13):1586-99
1	J:269861 Cargnin F, Kwon JS, Katzman S, Chen B, Lee JW, Lee SK, FOXG1 Orchestrates Neocortical Organization and Cortico-Cortical Connections. Neuron. 2018 Dec 5;100(5):1083-1096.e5
1	J:184158 Chenaux G, Henkemeyer M, Forward signaling by EphB1/EphB2 interacting with ephrin-B ligands at the optic chiasm is required to form the ipsilateral projection. Eur J Neurosci. 2011 Nov;34(10):1620-33
1*	J:71338 Chung WW, Lagenaur CF, Yan YM, Lund JS, Developmental expression of neural cell adhesion molecules in the mouse neocortex and olfactory bulb. J Comp Neurol. 1991 Dec 8;314(2):290-305
1	J:226607 Clegg JM, Li Z, Molinek M, Caballero IM, Manuel MN, Price DJ, Pax6 is required intrinsically by thalamic progenitors for the normal molecular patterning of thalamic neurons but not the growth and guidance of their axons. Neural Dev. 2015;10(1):26
1	J:248927 Clements R, Turk R, Campbell KP, Wright KM, Dystroglycan Maintains Inner Limiting Membrane Integrity to Coordinate Retinal Development. J Neurosci. 2017 Aug 30;37(35):8559-8574
1	J:264980 Coffinier C, Jung HJ, Nobumori C, Chang S, Tu Y, Barnes RH 2nd, Yoshinaga Y, de Jong PJ, Vergnes L, Reue K, Fong LG, Young SG, Deficiencies in lamin B1 and lamin B2 cause neurodevelopmental defects and distinct nuclear shape abnormalities in neurons. Mol Biol Cell. 2011 Dec;22(23):4683-93
1	J:313341 Comer JD, Pan FC, Willet SG, Haldipur P, Millen KJ, Wright CV, Kaltschmidt JA, Sensory and spinal inhibitory dorsal midline crossing is independent of Robo3. Front Neural Circuits. 2015;9:36
1	J:197849 Deck M, Lokmane L, Chauvet S, Mailhes C, Keita M, Niquille M, Yoshida M, Yoshida Y, Lebrand C, Mann F, Grove EA, Garel S, Pathfinding of corticothalamic axons relies on a rendezvous with thalamic projections. Neuron. 2013 Feb 6;77(3):472-84
1*	J:274718 Diao Y, Cui L, Chen Y, Burbridge TJ, Han W, Wirth B, Sestan N, Crair MC, Zhang J, Reciprocal Connections Between Cortex and Thalamus Contribute to Retinal Axon Targeting to Dorsal Lateral Geniculate Nucleus. Cereb Cortex. 2018 Apr 1;28(4):1168-1182
1	J:306056 Doyle DZ, Lam MM, Qalieh A, Qalieh Y, Sorel A, Funk OH, Kwan KY, Chromatin remodeler Arid1a regulates subplate neuron identity and wiring of cortical connectivity. Proc Natl Acad Sci U S A. 2021 May 25;118(21):e2100686118
1	J:168258 Dwyer ND, Manning DK, Moran JL, Mudbhary R, Fleming MS, Favero CB, Vock VM, O'Leary DD, Walsh CA, Beier DR, A forward genetic screen with a thalamocortical axon reporter mouse yields novel neurodevelopment mutants and a distinct emx2 mutant phenotype. Neural Dev. 2011;6:3
1	J:311814 Eom TY, Stanco A, Guo J, Wilkins G, Deslauriers D, Yan J, Monckton C, Blair J, Oon E, Perez A, Salas E, Oh A, Ghukasyan V, Snider WD, Rubenstein JL, Anton ES, Differential regulation of microtubule severing by APC underlies distinct patterns of projection neuron and interneuron migration. Dev Cell. 2014 Dec 22;31(6):677-89
1	J:157201 Eto K, Kawauchi T, Osawa M, Tabata H, Nakajima K, Role of dual leucine zipper-bearing kinase (DLK/MUK/ZPK) in axonal growth. Neurosci Res. 2010 Jan;66(1):37-45
1	J:119469 Fouquet C, Di Meglio T, Ma L, Kawasaki T, Long H, Hirata T, Tessier-Lavigne M, Chedotal A, Nguyen-Ba-Charvet KT, Robo1 and robo2 control the development of the lateral olfactory tract. J Neurosci. 2007 Mar 14;27(11):3037-45
1*	J:19818 Franz T, Extra-toes (Xt) homozygous mutant mice demonstrate a role for the Gli-3 gene in the development of the forebrain. Acta Anat (Basel). 1994;150(1):38-44
1	J:215584 Gil-Sanz C, Landeira B, Ramos C, Costa MR, Muller U, Proliferative defects and formation of a double cortex in mice lacking Mltt4 and Cdh2 in the dorsal telencephalon. J Neurosci. 2014 Aug 6;34(32):10475-87
1	J:105160 Guenette S, Chang Y, Hiesberger T, Richardson JA, Eckman CB, Eckman EA, Hammer RE, Herz J, Essential roles for the FE65 amyloid precursor protein-interacting proteins in brain development. EMBO J. 2006 Jan 25;25(2):420-31
1	J:229411 Hakanen J, Salminen M, Defects in neural guidepost structures and failure to remove leptomeningeal cells from the septal midline behind the interhemispheric fusion defects in Netrin1 deficient mice. Int J Dev Neurosci. 2015 Dec;47(Pt B):206-15
1*	J:91247 Hirata T, Suda Y, Nakao K, Narimatsu M, Hirano T, Hibi M, Zinc finger gene fez-like functions in the formation of subplate neurons and thalamocortical axons. Dev Dyn. 2004 Jul;230(3):546-56
1	J:94593 Inaki K, Nishimura S, Nakashiba T, Itohara S, Yoshihara Y, Laminar organization of the developing lateral olfactory tract revealed by differential expression of cell recognition molecules. J Comp Neurol. 2004 Nov 15;479(3):243-56
1	J:249035 Kannan M, Bayam E, Wagner C, Rinaldi B, Kretz PF, Tilly P, Roos M, McGillewie L, Bar S, Minocha S, Chevalier C, Po C, Chelly J, Mandel JL, Borgatti R, Piton A, Kinnear C, Loos B, Adams DJ, Herault Y, Collins SC, Friant S, Godin JD, Yalcin B, WD40-repeat 47, a microtubule-associated protein, is essential for brain development and autophagy. Proc Natl Acad Sci U S A. 2017 Oct 31;114(44):E9308-E9317
1	J:221642 Klingler E, Martin PM, Garcia M, Moreau-Fauvarque C, Falk J, Chareyre F, Giovannini M, Chedotal A, Girault JA, Goutebroze L, The cytoskeleton-associated protein SCHIP1 is involved in axon guidance, and is required for piriform cortex and anterior commissure development. Development. 2015 Jun 1;142(11):2026-36
1*	J:99710 Kudo C, Ajioka I, Hirata Y, Nakajima K, Expression profiles of EphA3 at both the RNA and protein level in the developing mammalian forebrain. J Comp Neurol. 2005 Jul 4;487(3):255-69
1	J:217604 Lavado A, Ware M, Pare J, Cao X, The tumor suppressor Nf2 regulates corpus callosum development by inhibiting the transcriptional coactivator Yap. Development. 2014 Nov;141(21):4182-93
1*	J:96395 Lee S, Walker CL, Karten B, Kuny SL, Tennese AA, O'Neill MA, Wevrick R, Essential role for the Prader-Willi syndrome protein necdin in axonal outgrowth. Hum Mol Genet. 2005 Mar 1;14(5):627-37
1	J:325446 Lepiemme F, Stoufflet J, Javier-Torrent M, Mazzucchelli G, Silva CG, Nguyen L, Oligodendrocyte precursors guide interneuron migration by unidirectional contact repulsion. Science. 2022 May 20;376(6595):eabn6204
1*	J:104312 Li HP, Oohira A, Ogawa M, Kawamura K, Kawano H, Aberrant trajectory of thalamocortical axons associated with abnormal localization of neurocan immunoreactivity in the cerebral neocortex of reeler mutant mice. Eur J Neurosci. 2005 Dec;22(11):2689-96
1*	J:69842 Lustig M, Erskine L, Mason CA, Grumet M, Sakurai T, Nr-CAM expression in the developing mouse nervous system: ventral midline structures, specific fiber tracts, and neuropilar regions. J Comp Neurol. 2001 May 21;434(1):13-28
1	J:217046 Magnani D, Hasenpusch-Theil K, Benadiba C, Yu T, Basson MA, Price DJ, Lebrand C, Theil T, Gli3 controls corpus callosum formation by positioning midline guideposts during telencephalic patterning. Cereb Cortex. 2014 Jan;24(1):186-98
1*	J:236412 Mestres I, Chuang JZ, Calegari F, Conde C, Sung CH, SARA regulates neuronal migration during neocortical development through L1 trafficking. Development. 2016 Sep 1;143(17):3143-53
1	J:238369 Mihalas AB, Elsen GE, Bedogni F, Daza RA, Ramos-Laguna KA, Arnold SJ, Hevner RF, Intermediate Progenitor Cohorts Differentially Generate Cortical Layers and Require Tbr2 for Timely Acquisition of Neuronal Subtype Identity. Cell Rep. 2016 Jun 28;16(1):92-105
1	J:310398 Mire E, Hocine M, Bazellieres E, Jungas T, Davy A, Chauvet S, Mann F, Developmental Upregulation of Ephrin-B1 Silences Sema3C/Neuropilin-1 Signaling during Post-crossing Navigation of Corpus Callosum Axons. Curr Biol. 2018 Jun 4;28(11):1768-1782.e4
1*	J:74494 Nakashiba T, Nishimura S, Ikeda T, Itohara S, Complementary expression and neurite outgrowth activity of netrin-G subfamily members. Mech Dev. 2002 Feb;111(1-2):47-60
1	J:290851 Quintana-Urzainqui I, Hernandez-Malmierca P, Clegg JM, Li Z, Kozic Z, Price DJ, The role of the diencephalon in the guidance of thalamocortical axons in mice. Development. 2020 Jun 26;147(12):dev184523
1	J:234107 Saito Y, Miranda-Rottmann S, Ruggiu M, Park CY, Fak JJ, Zhong R, Duncan JS, Fabella BA, Junge HJ, Chen Z, Araya R, Fritzsch B, Hudspeth AJ, Darnell RB, NOVA2-mediated RNA regulation is required for axonal pathfinding during development. Elife. 2016;5:e14371
1	J:170671 Shibata M, Nakao H, Kiyonari H, Abe T, Aizawa S, MicroRNA-9 regulates neurogenesis in mouse telencephalon by targeting multiple transcription factors. J Neurosci. 2011 Mar 2;31(9):3407-22
1	J:110263 Smith KM, Ohkubo Y, Maragnoli ME, Rasin MR, Schwartz ML, Sestan N, Vaccarino FM, Midline radial glia translocation and corpus callosum formation require FGF signaling. Nat Neurosci. 2006 Jun;9(6):787-97
1	J:226502 Takagi T, Nishizaki Y, Matsui F, Wakamatsu N, Higashi Y, De novo inbred heterozygous Zeb2/Sip1 mutant mice uniquely generated by germ-line conditional knockout exhibit craniofacial, callosal and behavioral defects associated with Mowat-Wilson syndrome. Hum Mol Genet. 2015 Nov 15;24(22):6390-402
1	J:221658 Vithayathil J, Pucilowska J, Goodnough LH, Atit RP, Landreth GE, Dentate Gyrus Development Requires ERK Activity to Maintain Progenitor Population and MAPK Pathway Feedback Regulation. J Neurosci. 2015 Apr 29;35(17):6836-48
1*	J:143543 Vogel T, Gruss P, Expression of Leukaemia associated transcription factor Af9/Mllt3 in the cerebral cortex of the mouse. Gene Expr Patterns. 2009 Feb;9(2):83-93
1	J:171771 Wu CS, Zhu J, Wager-Miller J, Wang S, O'Leary D, Monory K, Lutz B, Mackie K, Lu HC, Requirement of cannabinoid CB(1) receptors in cortical pyramidal neurons for appropriate development of corticothalamic and thalamocortical projections. Eur J Neurosci. 2010 Sep;32(5):693-706
1	J:327333 Yang KY, Zhao S, Feng H, Shen J, Chen Y, Wang ST, Wang SJ, Zhang YX, Wang Y, Guo C, Liu H, Tang TS, Ca(2+) homeostasis maintained by TMCO1 underlies corpus callosum development via ERK signaling. Cell Death Dis. 2022 Aug 4;13(8):674